The Las Vegas, Nevada Strip Hotel Labor Relations Collection comprises legal documents, correspondence, and human resources manuals and pamphlets related to labor in the hospitality industry on the Las Vegas Strip in Nevada from 1963 to 2008. The majority of documents involve the Culinary Union, the Bartenders Union, the Teamsters Union, MGM Mirage affiliated hotel casinos, the Dunes Hotel, and the Sands Hotel and Casino.

The McCall Family Papers are comprised primarily of family photographs and correspondence from 1910-1970. The materials concentrate on Quannah McCall and his daughter, Connie McCall, both were well known dentists in Southern Nevada. The materials also contain letters, postcards, holiday cards, and birth, death, and marriage certificates, as well as school commencement announcements for family members.

The Ferron and Bracken Photograph Collection depicts Southern and Central Nevada and other western states from 1890 to 1961. The photographs primarily depict the development and growth of early Las Vegas, Nevada; mines and mining operations in Southern and Central Nevada; towns and mines in Nevada; and the Hoover (Boulder) Dam and the Colorado River.

The Archie C. Grant Photograph Collection (1914-1968) contains black-and-white photographs of Nevada politician Archie C. Grant. The materials include photographs of Grant with the Las Vegas Housing Authority at groundbreaking ceremonies, the University of Nevada Board of Regents, and with other Nevada politicians. Materials also contain early photographs of the University of Nevada, Las Vegas campus, including the dedication of Maude Frazier Hall.

The Chester Longwell Photograph Collection consists of 608 black-and-white photographic prints dating from approximately 1910 to 1930. The images primarily depict the Longwell family's excursions in the Southern Nevada region, primarily to Mount Charleston, Nevada. Also included are images of Southern Nevada mines and mining towns, as well as Pubelo Grande de Nevada, the Lost City. The remaining images depict geological formations and features, as well as forestry and nature scenes in Nevada and Arizona.

The Harrah’s Entertainment, Inc. Photograph Collection contains black-and-white and color photographic prints, negatives, postcards, and slides of William "Bill" Harrah at events in Nevada between approximately 1930 and 1991. Also included are views of Harrah’s Nevada properties including Harrah’s Lake Tahoe Hotel and Casino, Harrah’s Reno Hotel and Casino, and the Holiday Inn Hotel and Casino (that later became Harrah’s Las Vegas Hotel and Casino).

The Sister Klaryta Antoszewska Photograph Collection (1977-1991) consists of photographic slides that depict various Nevada, United States, and international nuclear test protests. The collection includes images of Sister Klaryta Antoszewska and Sister Rosemary Lynch, as well as images of the Lenten Desert Experience and numerous protests at the Nevada Test Site. Also included are images of nuclear testing, soldiers, and anti-nuclear testing promotional materials.