The Helen M. Shepp Photograph Collection contains photographs of community organizations, entertainers, and significant figures in Las Vegas, Nevada from 1950 to 1964. The collection includes photographs of the American Association of the United Nations, the Navy Mother's Club, and the Women's Democratic Club. The collection also includes photographs of Nevada politicians and entertainers.

The Byrd Wall Sawyer Collection primarily consists of Byrd's research files on Nevada from 1930 to 1970. The materials concentrate on her monograph, "Nevada Nomads," as well as her co-authored textbook, "Here is Nevada." The collection also includes speeches, journal articles, memos, research note cards and papers, correspondence, informational booklets and pamphlets, maps, photographs, audiovisual materials, and newspaper articles and clippings.

The Liberace Fan Memorabilia Collection (1944-2004) consists of fliers, brochures, newspaper articles, show programs, and collectibles chronicling the life and career of famed Las Vegas, Nevada entertainer Liberace. Materials from the Liberace Foundation, various fan clubs, and the Liberace Museum in Las Vegas comprise the bulk of the collection.

The El Rancho Vegas Collection (1953-1961) is comprised of materials and memorabilia from the El Rancho Vegas Hotel collected by former hotel controller, Frank Watts. Records include financial documents including endorsed checks to performers at the resort. Other items included unused stationary, copies of the menu, and memorabilia from the hotel. The collection also contains a bathmat, hangers, and a drinking glass from the hotel.

The Nye County, Nevada Photograph Collection contains photographs from Nye County, Nevada from 1880 to 1990. The collection includes a wide variety of photographs that document the activities, landmarks, geographical features, towns, ranches, and families of Nye County. The collection covers the areas of Amargosa Valley, Ash Meadows, Beatty, Duckwater, Gabbs, Goldfield, Kawich Mountains, Manhattan, Pahrump, Round Mountain, Rhyolite, Smoky Valley, Springdale, Tecopa, Tonopah, and Twin Springs. The activities documented include mining, prospecting, herding animals, schooling, ranching, building construction, railroad construction, and hunting and fishing.

The Minnie Perchetti Photograph Collection (approximately 1902-1959) consists of black-and-white photographic prints and negatives of Tonopah, Nevada and documents Tonopah in the first half of the 20th century. The photographs depict mines, events, buildings, people, and landscapes in Tonopah, Nevada. Included in the collection are photographs of the 1923 fire in Goldfield, Nevada.

Victor Kunkel Collection of Artifacts (1964-1971) consists of the following items: dice sets from Las Vegas hotels; Clark County deputy badges; and a coin and currency collection from all over the world.