The Dennis McBride Erotica Collection (approximately 1950s-2003) consists of heterosexual and homosexual erotic photograph, drawings, and magazines. The collection also contains reproductions of early pornographic materials from the 1930s and 1940s and a stereoscope viewer with image inserts depicting nude females. This collection provides insight into erotica and pornography dating from the mid- to late- twentieth century.

The Helen M. Shepp Photograph Collection contains photographs of community organizations, entertainers, and significant figures in Las Vegas, Nevada from 1950 to 1964. The collection includes photographs of the American Association of the United Nations, the Navy Mother's Club, and the Women's Democratic Club. The collection also includes photographs of Nevada politicians and entertainers.

The Thomas J. Osborne Photograph Collection (approximately 1890-1930) consists of black-and-white photographic prints, negatives, and slides. Images depict the family of Thomas J. Osborne, his law office, the family home, and views of the town of Pioche, Nevada and surrounding areas. Several images depict local mines and unidentified mine workers.

The Liberace Fan Memorabilia Collection (1944-2004) consists of fliers, brochures, newspaper articles, show programs, and collectibles chronicling the life and career of famed Las Vegas, Nevada entertainer Liberace. Materials from the Liberace Foundation, various fan clubs, and the Liberace Museum in Las Vegas comprise the bulk of the collection.

The Nan Doughty Family Collection dates from 1845 to 1993 and documents Doughty's personal and professional life. She collected correspondence and papers related to her extended family members including Sallie Bradford, Seymour Kimball Bradford, William Hillman Shockley, and May Bradford Shockley. The collection also includes papers from her father, Thorwald A. Siegfriedt, and her mother, Lou-vee Bradford Siegfried. Doughty used her family histories to write historical essays about early Nevada. The collection includes her professional papers as well as drafts and correspondence related to her writings.

The Minnie Perchetti Photograph Collection (approximately 1902-1959) consists of black-and-white photographic prints and negatives of Tonopah, Nevada and documents Tonopah in the first half of the 20th century. The photographs depict mines, events, buildings, people, and landscapes in Tonopah, Nevada. Included in the collection are photographs of the 1923 fire in Goldfield, Nevada.

Victor Kunkel Collection of Artifacts (1964-1971) consists of the following items: dice sets from Las Vegas hotels; Clark County deputy badges; and a coin and currency collection from all over the world.