The Arlene Mathews Smith Photograph Collection (1910-1945) is comprised of photographs of people and places in and around Panaca, Nevada. The collection contains a photograph album featuring Smith, her family and friends, and various residents and events around the area. Included as part of the collection are photographs from the Last Frontier Hotel in Las Vegas, Nevada.

The James C. Shaw Collection on Hotel Dining consists of materials relating to hotel dining from hotels in Las Vegas, Nevada and other North American cities during the 1980s. The collection features room service menus, hotel restaurant menus, and information regarding banquet services.

The Lorelle Nelson Collection on Atomic Testing is comprised of newspaper clippings, magazine and journal articles, correspondence, press releases, fact sheets, fliers, informational handouts and booklets, and newsletters from approximately 1980 to 2009 concerning nuclear weapons testing at the Nevada Test Site, throughout the United States, and internationally. The collection includes information about anti-nuclear groups, committees, and associations, as well as information on the effects of radiation, nuclear fallout, lawsuits and court cases, events and protests, conferences, and local news coverage.

The Las Vegas, Nevada Gay, Lesbian, Bisexual, Transgender, and Queer/Questioning (LGBTQ) Collection documents the social and political activities of Las Vegas, Nevada's LGBTQ community from 1955 to 2020. The collection includes hundreds of newspaper articles about LGBTQ issues, ranging from AIDS to Nevada legislation. The collection also documents the presence of the LGBTQ community in Las Vegas, including material from gay bars, nightclubs, social clubs, advocacy and political organizations, entertainers, and student groups. Previously known as the Las Vegas Gay, Lesbian, Bisexual, and Transgender Collection.

The UNLV Libraries Collection of Prints, Lithographs, and Illustrations (approximately 1840-1950) contains visual artwork depicting Native Americans, white settlers, and various railroad and mining activities in the American West during the 19th century. The collection also contains artwork depicting various games, the act of gambling, and advertisements. Materials include prints, illustrations, lithographs, and newspaper clippings.

The Dennis McBride Collection of Gay Erotica (1960-2006) contains a selection of pornographic publications, three VHS tapes of erotic films, and photographic prints mail ordered from gay erotica or physique photography studios. The three studios represented in this collection are Alexander Studio, Sierra Domino Studio, and Third World Studio.

The Tom and Erma Godbey Photograph Collection is comprised of thirteen black-and-white photographic prints and negatives from 1934 to 1944. The photographs depict the Godbey family participating in parades and other events in Boulder City, Nevada and Las Vegas, Nevada.