The Henry C. Wieking Photograph Collection contains black-and-white photographic prints and negatives, as well as postcards of Las Vegas, Nevada between approximately 1920 and 1940. These images primarily depict Wieking and his family in front of the Las Vegas Mormon Fort and Hoover Dam (Boulder Dam). Other photographs include Six Companies and United States Bureau of Reclamation vehicles, Mount Charleston, the Colorado River, Black Canyon, and desert scenes. The remaining images depict Barstow and Death Valley, California; and a Grand Canyon bridge in Arizona.

The Sands Hotel Photograph Collection depicts entertainers, celebrities, events, amenities, and staff at the Sands Hotel in Las Vegas, Nevada from approximately 1952 to 1980. The photographs primarily depict entertainers like Frank Sinatra, Dean Martin, and the Copa Girls performing in the Copa Room, the showroom of the Sands Hotel. The photographs also depict patrons gambling, events held in the Sands Hotel's ballrooms, banquets, the pool, rooms in the hotel, as well as Jack Entratter, the hotel'’s director of entertainment.

The Timothy Peters Postcard Collection consists of postcards dating from 1905 to 1992. The postcards feature playing cards and card games. There are advertisements, illustrations, quotes, and scenes from games that all contain playing cards in some way.

The Nevada Political Buttons Collection contains campaign buttons from 1972 to 2000. The collection includes buttons for political candidates at the federal, state, and local levels, including Bill Clinton and Al Gore for President of the United States, Harry Reid for United States Senate from Nevada, Bob Miller for governor of Nevada, and various candidates for Nevada's state legislature and other elected positions. The collection also contains buttons from some of Nevada's local political organizations, including Las Vegas, Nevada's branch of the Culinary Union, Nevada Fair Pay Coalition, and No Nuclear in Nevada.

The William S. Park Photograph Collection (approximately 1870-1960) consists of black-and-white photographic prints and negatives of the families of William S. Park, John S. Park, and John William Park, as well as photographs of the Thomas children, half-siblings of John William Park's daughter Virginia. The majority of the images show locations in Las Vegas, Nevada with a smaller number taken in Kentucky, Oklahoma, Colorado, and California. Also included are three photograph albums of William S. and John William Park as children.

The Claudine Williams Photograph Collection (approximately 2007-2009) consists of nine optical disks containing ninety-eight digital surrogate images dating between 1940 and 2000. The images primarily portray Claudine Williams in publicity images for various hotel and casinos Williams and her husband owned alongside prominent individuals, including Dean Martin, Hillary and Bill Clinton, and Robert Reich. Other images depict Williams in her youth and with her family members. Additional materials include images of Williams’ business cards, articles in various Las Vegas and Nevada magazines and newspapers on Williams, and images of properties Williams operated.

The Elizabeth Harrington Photograph Collection (approximately 1910-1959) is comprised of black-and-white and color photographic prints and negatives. The images primarily depict the Kiwanis Club in Las Vegas, Nevada, as well as the Potosi mine in Nevada. Other images depict early Helldorado parades, airplanes at Anderson Field (Rockwell Field), and First State Bank employees. Also included are images of locations in Las Vegas, including Las Vegas grammar schools, the El Portal Theater, El Rancho Vegas, Fremont Street, Overland Hotel, and the Old Arizona Club. Additional images include portraits of Maude Frazier, Ray Lyman, and Arthur Harrington.