The Gertrude and Roosevelt Toston Photograph Collection is comprised of digital surrogates of photographic prints, slides, and ephemera documenting Gertrude and Roosevelt Toston's lives in Las Vegas, Nevada from 1958 to 2002. The collection mainly documents Roosevelt Toston's career as a newscaster for KLAS-TV and Gertrude Toston's involvement with the Delta Sigma Theta Sorority. Other images in this collection include photographs of Roosevelt Toston's childhood home in Epps, Louisiana and photographs of Gertrude Toston with her stepfather, Reverend Leo A. Johnson.

The William Hillman Shockley Photograph Collection (1875-1925, 1951) contains black-and-white photographs documenting mining operations at the Mount Diablo Mine and Millworks in Candelaria, Nevada. It also includes photographs of nearby operations including the Northern Belle Mine and the Princess Mill. The collection contains photographs of Shockley, his son, William Bradford Shockley, as an infant, as well as images of Shockley’s brothers, Walter A. Shockley and George Shockley.

The Frank F. Watts Collection of Casino Memorabilia (1880-1990) consists of gaming tokens and chips, matchbooks, and other memorabilia from Nevada and international casinos. The collection also contains items related to early Northern Nevada history including a salt ledger from 1880 as well as a wanted poster from 1913.

The UNLV Libraries Collection on Casino Game Management is comprised of management training guides and manuals used in casino management and operations dating from 1982 to 1999 from different hotel casinos primarily from Las Vegas, Nevada. Guides and manuals cover topics such as casino floor supervision and dealer/staff training for table games. The collection includes published guides as well as internal casino procedural manuals and employee handbooks from hotels such as Circus Circus, Mandalay Bay, the Monte Carlo, the Rio, and Harrah's (Laughlin, NV).

The Si Zentner Collection of Music Scores consists of copyright agreements and original music scores from the career of musician Si Zentner. The manuscripts span from 1957 through 1996.

The Arlene Mathews Smith Photograph Collection (1910-1945) is comprised of photographs of people and places in and around Panaca, Nevada. The collection contains a photograph album featuring Smith, her family and friends, and various residents and events around the area. Included as part of the collection are photographs from the Last Frontier Hotel in Las Vegas, Nevada.

The UNLV Libraries Collection of Prints, Lithographs, and Illustrations (approximately 1840-1950) contains visual artwork depicting Native Americans, white settlers, and various railroad and mining activities in the American West during the 19th century. The collection also contains artwork depicting various games, the act of gambling, and advertisements. Materials include prints, illustrations, lithographs, and newspaper clippings.