The Amy Ayoub Papers (1906-2022) document the life and career of Amy Ayoub, a long-time resident of Las Vegas, Nevada. The collection consists of correspondence, photographs, newspaper clippings, research, and other material that document the numerous facets of Ayoub's life. The collection covers many areas: Ayoub's early childhood; her family, including father Bobby Ayoub and stepfather Raymond Sutton; her financial consulting career and political work; her experience working as a prostitute in Nevada and subsequent documentary about being sex trafficked and working in brothels; time spent as the first female Nevada Athletic Commissioner; and more. Digital files include audio and video files of Mike Tyson's 2002 licensure hearing, and video of Ayoub's testimony before the Nevada State Assembly Judiciary Committee for Assembly Bill 67 in 2013. There are also digitized photographs that Ayoub used for the documentary The Zen Speaker: Breaking the Silence.

The Robert Lang Professional Papers (1976-2020) mainly contain urban planning research and reports from former University of Nevada, Las Vegas (UNLV) professor and public policy expert Robert Lang. Materials represent different public policy related projects and issues Lang worked on when he was employed with the Fannie Mae Foundation in Washington, D.C., and Brookings Mountain West and the Lincy Institute at UNLV. Materials also include Lang's teaching files which include course syllabi, class presentation slides, and course readers. Research, notes, and drafts of Lang's books including Boomburbs: The Rise of America's Accidental Cities, Edgeless Cities: Exploring the Elusive Metropolis, and Blue Metros, Red States: The Shifting Urban-Rural Divide in America's Swing States are also represented in the collection. The collection also includes documentation for invited conferences and events documenting different conferences and events, copies of Black's Guide for commercial real estate in the United States.

The Nan Doughty Family Collection dates from 1845 to 1993 and documents Doughty's personal and professional life. She collected correspondence and papers related to her extended family members including Sallie Bradford, Seymour Kimball Bradford, William Hillman Shockley, and May Bradford Shockley. The collection also includes papers from her father, Thorwald A. Siegfriedt, and her mother, Lou-vee Bradford Siegfried. Doughty used her family histories to write historical essays about early Nevada. The collection includes her professional papers as well as drafts and correspondence related to her writings.

The Shar Rednour and Jackie Strano Papers on S.I.R. Productions (1981-2015) contain the personal and professional papers of Rednour and Strano, two lesbian filmmakers, writers, and activists from the 1990s until the 2010s. The collection contains the personal papers of both Rednour and Strano, including correspondence between the pair before they married in 2006. The collection also contains the professional files of Rednour and Strano in their capacity as creators of SIR (Sex, Indulgence, and Rock and Roll) Video in 1998. Materials include financial documents, correspondence, scripts and editing notes, crew information, publicity photographs, and direct order forms for S.I.R. Productions. In addition to records on SIR Video, the collection also contains a number of sex-positive and lesbian, gay, bisexual, transgender, and queer (LGBTQ) publications from the LGBTQ scene in San Francisco, California during the 1990s.

The Story of Classic Las Vegas Oral History Interviews (approximately 1950-2006) is comprised of raw and edited video recordings of oral history interviews used for The Story of Classic Las Vegas documentary which was produced, directed, and edited by Lynn Zook. The documentary offers first person historical overviews of what it was like to live in Las Vegas, Nevada from the 1920s to the 1970s. Individuals interviewed include a wide range of community members of the Las Vegas Valley including business owners, educators, entertainers, politicians, gaming professionals, casino workers, and activists. Materials also include a media kit with promotional materials and interview transcript for one of the interviewees, Betty Willis.

The University of Nevada, Las Vegas Solar Decathlon Records (2013-2021) are comprised of records documenting the University of Nevada, Las Vegas's participation in the U.S. Department of Energy (DOE) Solar Decathlon collegiate competition. The collection includes records created by the 2013, 2017, and 2020 UNLV teams (Team Las Vegas) in designing and building their respective competition entries: DesertSol, Sinatra Living, and Mojave Bloom. Records include competition application files, working project files, As-Built submittal packets, and promotional and marketing files for the competition. The majority of records in this collection represent the 2017 competition. Archived websites and social media accounts associated with Team Las Vegas and the Solar Decathlon competition are also included in the collection. The records document Team Las Vegas's efforts in designing and building energy efficient homes for the Solar Decathlon competition.

The Wilbur and Toni Clark Papers date from 1944 to 1991, with the bulk from 1953 to 1963 and document the lives of Wilbur and Toni Clark in Las Vegas, Nevada and the development of the Desert Inn Hotel and Casino. The collection includes correspondence from Wilbur Clark to those he identified as important individuals including government officials and celebrities. It also includes materials related to Clark’s plan of building luxury apartments near the Desert Inn, and newspaper clippings and scrapbooks about the Clarks and the Desert Inn. The collection contains some audiovisual materials including Wilbur and Toni Clark's home movies, news footage, and film footage of Las Vegas, Nevada and the Desert Inn.