The Howard Hughes Professional and Aeronautical Photographs contain black-and-white photographs of businessman and entrepreneur Howard Hughes and his companies from 1916 to 1997. The photographs primarily depict Hughes alongside his aircraft, including the XF-11 prototype reconnaissance plane and the HK-1 Hercules, better known as the "Spruce Goose" or "Flying Boat." The photographs also cover the companies owned by Hughes, including Hughes Tool Company, Hughes Aircraft Company, Hughes Electronics Corporation, and RKO Pictures.

The Robert Woodruff Photograph Collection (1900s-1970s) consists of ninety-seven black-and-white photographs of locations and events in Clark County, Nevada. Locations include Las Vegas, Henderson, and Searchlight, Nevada, as well as the Hoover Dam. The majority of the images were taken between 1934 and 1962.

The Shar Rednour and Jackie Strano Papers on S.I.R. Productions (1981-2015) contain the personal and professional papers of Rednour and Strano, two lesbian filmmakers, writers, and activists from the 1990s until the 2010s. The collection contains the personal papers of both Rednour and Strano, including correspondence between the pair before they married in 2006. The collection also contains the professional files of Rednour and Strano in their capacity as creators of SIR (Sex, Indulgence, and Rock and Roll) Video in 1998. Materials include financial documents, correspondence, scripts and editing notes, crew information, publicity photographs, and direct order forms for S.I.R. Productions. In addition to records on SIR Video, the collection also contains a number of sex-positive and lesbian, gay, bisexual, transgender, and queer (LGBTQ) publications from the LGBTQ scene in San Francisco, California during the 1990s.

The University of Nevada, Las Vegas Division of Educational Outreach Records (1971-2019) contain correspondence, planning information, promotional materials, photographs, and newspaper clippings about the history of the division and commemorative events such as the 25th and 40th anniversaries. The majority of the collection materials are comprised of course catalogs, directories, student journals, member handbooks, scrapbooks, and council meeting minutes for the division's lifelong learning programs for nontraditional students: the Extended Education Center for Lifelong Learning (EXCELL) and the Osher Lifelong Learning Institute (OLLI). Materials also include digital files of jazz performances from OLLI's Jazz Appreciation class, a video interview about OLLI, and recording of an OLLI panel featuring World War II veterans.

The University of Nevada, Las Vegas Solar Decathlon Records (2013-2021) are comprised of records documenting the University of Nevada, Las Vegas's participation in the U.S. Department of Energy (DOE) Solar Decathlon collegiate competition. The collection includes records created by the 2013, 2017, and 2020 UNLV teams (Team Las Vegas) in designing and building their respective competition entries: DesertSol, Sinatra Living, and Mojave Bloom. Records include competition application files, working project files, As-Built submittal packets, and promotional and marketing files for the competition. The majority of records in this collection represent the 2017 competition. Archived websites and social media accounts associated with Team Las Vegas and the Solar Decathlon competition are also included in the collection. The records document Team Las Vegas's efforts in designing and building energy efficient homes for the Solar Decathlon competition.

The Mike O'Callaghan Professional Papers (1943, 1968-2004) mainly consist of research files gathered by Mike O'Callaghan in his post-political capacity as executive editor of the Las Vegas Sun as well as owner and publisher of the Henderson Home News, Boulder City News, and Green Valley News. The papers also contain handwritten and typewritten drafts of O'Callaghan's "Where I Stand" article for the Las Vegas Sun, along with his reporter's notebooks, monthly planners, and photographic prints. The research files cover a wide variety of topics, including but not limited to environmental issues; nuclear waste; state and local politics; military and veterans affairs; foreign relations including Israel, Iraq, and Korea; and education. The collection also contains copies of speeches given by O'Callaghan as the 23rd Governor of Nevada between 1971 and 1979, some of which contain handwritten notations.

The Amy Ayoub Papers (1906-2022) document the life and career of Amy Ayoub, a long-time resident of Las Vegas, Nevada. The collection consists of correspondence, photographs, newspaper clippings, research, and other material that document the numerous facets of Ayoub's life. The collection covers many areas: Ayoub's early childhood; her family, including father Bobby Ayoub and stepfather Raymond Sutton; her financial consulting career and political work; her experience working as a prostitute in Nevada and subsequent documentary about being sex trafficked and working in brothels; time spent as the first female Nevada Athletic Commissioner; and more. Digital files include audio and video files of Mike Tyson's 2002 licensure hearing, and video of Ayoub's testimony before the Nevada State Assembly Judiciary Committee for Assembly Bill 67 in 2013. There are also digitized photographs that Ayoub used for the documentary The Zen Speaker: Breaking the Silence.