The Yucca Mountain Environmental Safety Collection (1970-2011) consists of reports and impact studies collected by Clark County's Nuclear Waste Division library for documenting Yucca Mountain's potential health and safety risks to Southern Nevada. The reports contain documents pertaining to potential environmental, health, financial, and safety risks from the Yucca Mountain Nuclear Waste Repository, which is located in Nye County, Nevada. The collection contains scientific and social studies in support of and opposition to the site. The bulk of the collection includes licensing reports, site selection studies, and impact studies from transporting, storing, and handling radioactive waste and spent nuclear fuel.

The collection is comprised of architectural drawings (1952-1997) completed by American architect, Ethan Jennings Jr. and/or his architectural firm, Ethan Jennings Jr., AIA, CSI and includes Jenning's work from the firm of John Badgley, AIA, where Ethan Jennings Jr. worked in Southern California during the 1950s, as well as work Jenning's completed with Americo Inc., and Tolosa Group. The collection contains 217 sets of drawings, 6 boxes of project records, and 8 flat files of oversized material from over 200 different projects primarily located in California with some projects located in the Las Vegas area. The materials feature hand-drawn architectural drawings, ranging from preliminary sketches to construction documents. The drawings also contain work from consultants, engineers, and other architects who collaborated on the development of the various projects. The drawings include: commercial, industrial, professional, civic, residential, and religious buildings of varying scales, such as libraries, apartments, warehouses, office developments, schools, military buildings, churches, and custom single-family homes located throughout California and Las Vegas. The drawings also include a number of additions, remodels, and renovations. The collection also contains project records like structural calculations and drawings, project manuals and specifications, bid documents, and professional correspondence.

The Sister Klaryta Antoszewska Photograph Collection (1977-1991) consists of photographic slides that depict various Nevada, United States, and international nuclear test protests. The collection includes images of Sister Klaryta Antoszewska and Sister Rosemary Lynch, as well as images of the Lenten Desert Experience and numerous protests at the Nevada Test Site. Also included are images of nuclear testing, soldiers, and anti-nuclear testing promotional materials.

The Gay and Lesbian Community Center of Southern Nevada Photograph Collection contains mainly candid photographs of events and individuals affiliated with the Las Vegas-based Gay and Lesbian Community Center of Southern Nevada (GLCCSN) dating from 1993 to 2000. Photographs depict events honoring prominent members of the gay, lesbian, bisexual, transgender, and queer community; meetings at GLCCSN; and candidate nights for members of the community running for public office. The collection also includes a number of photographs of the Freedom to Marry celebration at the GLCCSN and the Gay Pride Las Vegas festival from 1998 to 1999.

The Michael McKensie Pratt Professional Papers (approximately 1950-2021) contain costume designs, musical selections, and synopsis for shows that Pratt worked on in Las Vegas, Nevada including 90 Degrees & Rising, Les Folies Chic, and Jubilee!. The collection also contains souvenir show programs for cabaret shows performed in Paris, France and Las Vegas, Nevada, including Lido de Paris, Casino de Paris, Bal du Moulin Rouge, and Folies Bergere. Materials also include copies of Pratt's curriculum vita and swing bible used by Pratt when he was the co-company manager for Jubilee!. Also included are video recordings of shows Pratt choreographed and an archived version of Pratt's personal website.