The Wayne Cronister Photograph Collection depicts towns in Southern Nevada from 1905 to 1950. The photographs primarily depict Fremont Street in Las Vegas, Nevada and the construction of the Hoover (Boulder) Dam on the Colorado River. The photographs also include the Union Pacific Railroad Depot in Las Vegas, Nevada, the abandoned town of Rhyolite, Nevada, and a mining camp in El Dorado Canyon.

The Murl Emery Photograph Collection consists of seventeen black-and-white photographic reprints of ferries and recreational activities near Searchlight, Nevada on the Colorado River taken from approximately 1910 to 1946, and reprinted from approximately 1970 to 2004.

The Lorenzo Romans Papers (1875-1965) are comprised of photographs, newspaper clippings, a family photograph album, a diary, a diploma, and related ephemera. The materials were owned by Lorenzo Romans, a California real estate developer who moved to Las Vegas late in life after a short visit to Helen Stewart's Las Vegas Rancho in 1894.

The Thomas J. Osborne Photograph Collection (approximately 1890-1930) consists of black-and-white photographic prints, negatives, and slides. Images depict the family of Thomas J. Osborne, his law office, the family home, and views of the town of Pioche, Nevada and surrounding areas. Several images depict local mines and unidentified mine workers.

The Ernest Mitchell Pratt Photographs (approximately 1932-1936) consist of black-and-white photographic prints, signed and unsigned, taken by Pratt while Hoover Dam was under construction. Many prints are signed and mounted, and two are noted as award-winning photographs shown at the Annual International Salon of Camera Pictorialists in Los Angeles, California. There are additional working prints included alongside the final prints for most of the scenes. Also included in the collection is one small photograph of Pratt. This collection was formerly known as the Price Photograph Collection.

The Paul May Photograph Collection (1969) consists of black-and-white and color photographic prints. The images primarily depict Nevada Assemblyman Paul May alongside Nevadan senators and congressmen, including Senator Paul Laxalt. Other images are portraits of May.