Collection is comprised of correspondence, speeches, essays, meeting minutes, photographs, research materials, publications, press clippings, awards, and event programs (1941-2011) that document the life of Henry Schuster, and his work with his wife Anita. Materials are mainly related to the Holocaust and to Holocaust memory and survivor organizations (especially the Holocaust Survivor's Group of Southern Nevada, which the couple founded, and L’Œuvre de Secours aux Enfants). Genealogical information is also included, as well as records of Henry Schuster’s time in the U.S. Army and his studies at the Manhattan Technical Institute.

The Pueblo Grande de Nevada Manuscript Collection (1924-1983) contains journal articles, photocopies of artifact inventories, reports, correspondence, and field notes related to the Pueblo Grande de Nevada archaeological site located in the Overton Valley of Southern Nevada. The bulk of the materials are related to Mark R. Harrington's archaeological reports, journal articles, and data from sites throughout the Overton and Moapa valleys. The collection also includes materials related to the Boulder Dam Park Museum (Lost City Museum of Archaeology) located in Overton, Nevada, which housed many of the artifacts and photographs from Harrington's archaeological sites.

The Las Vegas Art Museum Records (1952-2009) contain administrative files, press, marketing materials, and scrapbooks that document the history of the Las Vegas Art Museum (LVAM). Collection materials include exhibition files, annual reports, financial statements, board meeting agendas and minutes, event invitations, press releases, and newspaper and magazine clippings documenting the museum's activities. Materials include photographs from museum events as well as photographs of artwork displayed as part of visiting and permanent exhibitions. Audio and video recordings include interviews with museum staff and local news coverage of events. Also included are architectural floor plans for the Sahara West Library, which was used as a gallery space for LVAM. Digital files in this collection include recordings and presentation slides from LVAM lectures with curators and artists. Other digital files include photographs from LVAM events and workings files from LVAM staff.