The Robert B. Griffith Collection (1928-1975) documents the work of Robert B. Griffith, an instrumental figure in the development of water resources in Las Vegas, Nevada, as well as the creation of McCarran International Airport and Nellis Air Force Base. The collection consists of Colorado River Commission papers, 1928 International Air Race documents, general correspondence, a feasibility study, an airport guide, American Legion papers, the memoirs of Alfred Merritt Smith, and death and burial records belonging to his father. The collection also includes slides from various countries, including the United States, Canada, Europe, Asia, and the Middle East.

The Sherwin "Scoop" Garside Papers comprise photographs and documents of Las Vegas Review-Journal writer and photographer Scoop Garside. The collection dates from 1930 to 1983 and includes publicity photos of the Old Spanish Trail, correspondence from the Nevada State Centennial Commission, history of mines (Tonopah, Goldfield, Bullfrog), copies of articles written by Garside, family photos and general photographs of people and places, negatives of Las Vegas, Nevada; Searchlight, Nevada; St. George, Utah; and several unlabeled negatives. The 2017 addition contains newspaper clippings, a scrapbook, Nevada Historical Quarterly, and information on Nevada historic preservation. There is also genealogical information on the Garside family.

The McCall Family Papers are comprised primarily of family photographs and correspondence from 1910-1970. The materials concentrate on Quannah McCall and his daughter, Connie McCall, both were well known dentists in Southern Nevada. The materials also contain letters, postcards, holiday cards, and birth, death, and marriage certificates, as well as school commencement announcements for family members.

The Nan Doughty Photograph Collection (1870-1987) consists of approximately 960 black-and-white and color photographic prints, black-and-white photographic negatives, and black-and-white and color photographic slides, taken by Nanelia Doughty, family members, and friends.

The William S. Park Photograph Collection (approximately 1870-1960) consists of black-and-white photographic prints and negatives of the families of William S. Park, John S. Park, and John William Park, as well as photographs of the Thomas children, half-siblings of John William Park's daughter Virginia. The majority of the images show locations in Las Vegas, Nevada with a smaller number taken in Kentucky, Oklahoma, Colorado, and California. Also included are three photograph albums of William S. and John William Park as children.

The Ernie W. and Lucille Marleau Cragin Photograph Collection contains photographic prints, negatives, and slides depicting early Las Vegas and Boulder City, Nevada events, buildings, and people between approximately 1900 and 1950.

The Las Vegas Ambassadors Collection (1968-1985) primarily consists of a scrapbook, newspaper articles, and photographs documenting the activities of the Las Vegas Ambassadors youth singing group. The materials were compiled by Harry LaFavor, the Ambassadors' business manager, who co-founded the group with Norman Kaye and Richie Astone to promote a positive image of Las Vegas. The collection also includes a songbook, vinyl record and ¼” tape recording, and promotional materials.