The Robert B. Griffith Collection (1928-1975) documents the work of Robert B. Griffith, an instrumental figure in the development of water resources in Las Vegas, Nevada, as well as the creation of McCarran International Airport and Nellis Air Force Base. The collection consists of Colorado River Commission papers, 1928 International Air Race documents, general correspondence, a feasibility study, an airport guide, American Legion papers, the memoirs of Alfred Merritt Smith, and death and burial records belonging to his father. The collection also includes slides from various countries, including the United States, Canada, Europe, Asia, and the Middle East.

The Jeanne Russell Janish Papers span the years 1833 through 1994 with an emphasis on 1894 to 1994. The materials of the illustrator and watercolorist include her school records, research papers, diaries, and personal correspondence. There are two original book manuscripts, dried flowers, hand-woven rugs, a variety of art supplies and tools, and approximately 140 watercolor paintings and pencil sketches of various scenes and subjects, created in China, Florida, and the American Southwest.

The Clyde F. Merrick Photographic Slides (approximately 1971-1979) contain color photographic slides taken by Clyde F. Merrick, longtime resident of Las Vegas, Nevada. The majority of slides in this collection depict signs for different businesses around Las Vegas including the Las Vegas Strip and the Westside. Some of the businesses documented in this collection includes Fong's Garden, Leon's Shear Magic Beauty Salon, Lucas and Son's Antiques, Dick's Tricky Trikes, Mohan's Custom Tailors, the Twenty Grand Club, Owens TV Repair, and Caesars Palace. The collection also documents a variety of different types of businesses around Las Vegas including bars and nightclubs, beauty salons, car washes, gas stations, and restaurants. Merrick was also a car racing hobbyist and a number of slides in this collection depict what is presumed to be the Las Vegas Speedrome racetrack (later known the Las Vegas Motor Speedway). This collection also includes photographs of locations outside of Las Vegas and Southern Nevada.

The University of Nevada, Las Vegas (UNLV) Office of the President Records is comprised of documents used in daily matters of the Office of the President from approximately 1950 to 2007. The records in the collection document the expansion of the UNLV campus, and the academic and athletics programs offered by the university.

The William Flangas Srapbooks document his anti-smoking efforts in Nevada from 1974 to 2014. These materials include correspondence, articles, copies of assembly bills, newsletters related to smoking and health, and newsletters related to non-smokers.