The Bill Willard Photograph Collection depicts Las Vegas, Nevada, hotels and casinos in Las Vegas, the Las Vegas Valley, and Laughlin, Nevada from 1905 to 1919 and from 1940 to 1999. The photographs primarily depict hotels and casinos in Las Vegas, including the Sahara Hotel, Circus Circus Hotel and Casino, MGM Grand Las Vegas Hotel and Casino, Caesars Palace, Flamingo Hotel, and the Aladdin Hotel. The photographs also depict students at Nevada Southern University (predecessor of the University of Nevada, Las Vegas), the city of Las Vegas, industrial plants in Henderson and Apex, Nevada, and events in Laughlin, Nevada.

The George Laurence Ullom Photograph Collection (1915-1974) contains photographic prints and negatives created by Las Vegas, Nevada photographer George Laurence "Larry" Ullom. Larry owned and operated Ullom’s Desert Art Studio, which was located in Las Vegas, Nevada. The bulk of the collection consists of Ullom's wedding chapel photography. The collection also includes his photography work for the Bureau of Reclamation, the Agricultural Extension Service, and the Associated Press, Atlantic News, and Acme news bureaus.

The Gerald Schaffer Professional Papers (approximately 1949-1999) contain materials from Schaffer's time working as a political executive assistant, private sector consultant, and developer of commercial, residential, and gaming projects throughout Clark County, Nevada. The collection includes newspaper clippings, photographs, correspondence, and administrative files from Schaffer's time working as an executive assistant for Nevada Congressman Walter S. Baring Jr. Schaffer's work with organizations is represented through programs, photographs, and correspondence. Documents relating to his work as Commissioner of Public Housing on the Clark County Public Housing Authority, service as Clark County Planning Commissioner, and as a commercial and residential developer in Las Vegas are also present in the collection.

The Dennis McBride LGBTQ Poster and Sign Collection (1977-2018) contains posters and signs created by the Las Vegas, Nevada Lesbian, Gay, Bisexual, Transgender, and Queer/Questioning (LGBTQ) community, collected by historian Dennis McBride. These handmade and commercially printed signs cover events of particular interest to the Las Vegas, Nevada LGBTQ community, including social events, entertainment venues, political rallies, and Gay Pride events.

The Renee Diamond Papers date from 1972 to 2000 and consist primarily of political and professional materials including reports, correspondence, publications, newsletters, and planning documents collected by Diamond throughout her career. Diamond supported the feminist movement as a member of the National Organization for Women and held leadership roles in the Democratic party in Las Vegas, Nevada. The collection also documents Diamond’s campaigns for the Nevada State Assembly and includes material from her one term in the legislature.

Flora Dungan Papers (1929-1974) contain high school and university records, certificates, newspaper clippings, press releases, notes, correspondence, and booklets about her life and political activism in Nevada. Also included are Legislative materials, an audio cassette tape, a copy of the Nevada Constitution, and an oil painting of Flora Dungan.

The Las Vegas Review-Journal Photograph Collection depicts several events in Las Vegas, Nevada from 1935 to 1983 that were documented by Nevada’s largest newspaper, the Las Vegas Review-Journal. The photographs depict the fire at the Las Vegas School in 1935, the fire at the MGM Grand Hotel and Casino in 1980, an exhibition at the Lost City Museum in 1973, a memorial event honoring the first permanent school in Las Vegas in 1980, and an exhibition at the Nevada State Museum and Historical Society in 1983. The collection also contains photographs of some denizens of Las Vegas, including people at the Hughes Bar in Las Vegas, the last Union Pacific passenger train in Las Vegas, and schoolchildren at the Las Vegas School.