The S. R. Shapiro Collection (1799, 1960-1979) contains gaming instructions, pamphlets, menus, promotional material from travel agents and casinos, and correspondence from Las Vegas, Nevada casinos and casinos around the world. There is also a copy of a French natural history book titled Memories de la Societe d'histoire naturelle de Paris dated 1799. Inside the book are attached advertisements and lottery announcements from English newspapers.

The Edward Clark Papers (1930-1945) contain photographs, a newspaper clipping, an inaugural invitation, and a memorial address delivered in congress for Key Pittman, a United States Senator from Nevada. Also included are National Democratic Convention materials, a Rotary Club bulletin and souvenir booklet, and brochures for various attractions in the Washington, D.C. area.

The Kathy Quinn Papers on the Paiute Indians (1969-1971) consists of photograph negatives, a kinship chart, a cassette tape of Paiute vocabulary, family history, and a paper listing Paiute words and their meanings. Also included are the uses of various herbs and plants and a brief autobiography of Stella Smith of the Las Vegas Indian Village.

The Larry L. Hezzelwood Collection (1953-1954) contains correspondence pertaining to the creation of a titanium processing plant in Boulder City, Nevada as part of the Aero Metals Corporation of Las Vegas, Nevada. Larry L. Hezzelwood served as secretary and treasurer of the Aero Metal Coporation.

The Yucca Mountain Site Characterization Office collection (1958-2001) was assembled through a joint effort between the Nuclear Regulatory Commission (NRC) and the James R. Dickinson Library, University of Nevada, Las Vegas (UNLV) to provide public access to documentation and correspondence about the proposed high-level radioactive waste geologic repository site near Yucca Mountain, Nevada. Materials include technical reports, contractor reports, public hearing transcripts, safety evaluation reports, environmental impact statements, emergency plans, inspection reports, licensee event reports, and general communications. The collection includes documents from several other government entities such as the Yucca Mountain Site Characterization Office, Department of Energy, Office of Civilian Radioactive Waste Management (OCRWM), Nevada Nuclear Waste Storage Investigations (NNWSI), United States Geological Survey (USGS), Sandia National Laboratories, Lawrence Livermore National Laboratory, and Los Alamos National Laboratory.

The Katherine A. Spilde Papers on Native American Gaming include materials collected by anthropologist Katherine Spilde about Native American gaming and the greater gaming industry. The materials date from 1789 to 2015, with the bulk of materials dating from 1995 to 2010. Materials dating from the eighteenth and nineteenth centuries are reproductions of key court opinions and treaties concerning Native American rights and sovereignty. The majority of the materials document Native American gaming following the passage of the 1988 Indian Gaming Regulatory Act (IGRA). The papers detail Native American gaming enterprises both on and off reservations, the socioeconomic impact of gaming, and the legislative history of Native American gaming in the United States. The papers include research and subject files created by Dr. Spilde during her employment with the National Gambling Impact Study Commission (NGISC), the National Indian Gaming Association (NIGA), and the Harvard Project on American Indian Economic Development (HPAIED). The collection includes socioeconomic reports; testimonies; correspondence; memos; press releases; photographs; audiovisual materials; promotional materials from casinos and tourist attractions; brochures; fact sheets; summaries; booklets; pamphlets; advertisements; tourism materials; journal articles; legal briefs; legislative documents; court opinions; Dr. Spilde’s notes; presentations; packets, agenda, schedules, and itineraries from conferences; periodicals; Native American and community newspapers; and newspaper articles. The collection includes materials about over one hundred federally recognized Native American nations. Also included are materials that document the socioeconomic impact of gaming, the international gaming industry, criminal activities related to gaming, advertising about gaming and casinos, lotteries, internet gaming, compulsive gambling, and bankruptcy as a result of gambling.

The Claudine Williams Papers (1956-2009) contain awards, contracts, personal and business correspondence, newspaper clippings, and photographs pertaining to Las Vegas, Nevada businesswoman and philanthropist, Claudine Williams. The collection also includes extensive information on her hotel and gaming properties, including the Silver Slipper Gambling Hall, Holiday Casino, and Harrah's Hotel and Casino, as well as her honorary doctoral degree, medals, and audiovisual materials of interviews, news reports, and events.