The C. C. (Clio Cline) Mobley Photograph Collection (approximately 1911 to 1917) consists of sixteen black-and-white photographic prints with corresponding photographic negatives. The images depict the Las Vegas, Nevada Ranch while the Mobley family leased it from the Union Pacific Railroad during the period. The photographs depict the home, swimming pool, the Old Las Vegas Mormon Fort, and orchards and streams on the property.

The Lavinia Tom Myers Photographs, approximately 1945-1962, depict members of the Tom family on the Moapa Indian Reservation in Nevada. There are four images in this collection. The images consist of Tom family members in front of their home and on the surrounding land.

The Frances Intravia Photograph Collection (approximately 1948 to 1979) contains three black-and-white photographic prints. The images depict Albert and Arabell Lee Hafner, author of 100 Years on the Muddy, visiting the St. Thomas, Nevada townsite after the Lake Mead water levels dropped enough make it visible. One of the prints is an original from approximately 1948 to 1952, and the other two are reproductions of images taken during the same period.

The O. J. Fisk Photographs depict Paiute, Shoshone, and non-indigenous residents of Pahrump Valley and Ash Meadows, Nevada from approximately 1880 to 1939. The photographs primarily depict Paiute and Shoshone workers and their children, but they also include photographs of non-indigenous farmers and ranchers. The photographs also depict Chief Tecopa, a leader of the Southern Nevada Paiute, who lived from approximately 1815 to 1904.

The L. F. Manis Photographs contain photographic prints, photographic slides, and photographic negatives depicting Southern Nevada from approximately 1900 to 1969, with a bulk of the materials dating from 1930 to 1940. The photographs primarily depict the construction, dedication, and various parts of the Hoover (Boulder) Dam, including the dam's upstream and downstream faces, intake towers, spillways, bridges, crest, outlet works, visitors' accommodations, and powerhouse. The photographs also depict Lake Mead, the reservoir created by the Hoover Dam, and the Colorado River, which is dammed by the Hoover Dam. The photographs also include views of desert landscapes in the Southwestern United States, including in Nevada, Arizona, and Southern California. Also depicted in the photographs are the cities of Las Vegas, Nevada and Boulder City, Nevada, including prominent buildings like hotels, casinos, government buildings, and train depots.

The Edward G. Halligan Photograph Collection on the Nevada Test Site contains photographs of nuclear detonations at the Nevada Test Site from the 1960s. The photographs primarily depict aboveground nuclear explosions, but they also contain photographs of facilities, machinery, and personnel at the Nevada Test Site.

The Helen J. Stewart Photographs depict the Stewart Family from approximately 1860 to 1950. The photographs primarily depict Helen J. Stewart and her children as well as the Stewart Ranch (also know as the Las Vegas Ranch) in Southern Nevada. The photographs include the early Las Vegas, Nevada town site, landscapes of Southern Nevada and the American Southwest, mines and mining camps, railroads and railroad workers, the Las Vegas Fort (also known as the Old Mormon Fort), hotels and early businesses in Las Vegas, Native Americans and Native American artifacts, and postcards.