The early Las Vegas, Nevada photographs document early Euro-American settlers in the Las Vegas Valley and the development of the original Las Vegas town site from approximately 1900 to 1940. The photographs depict the Union Pacific Railroad depot, early businesses on Fremont Street, the Clark County Courthouse, saloons, hotels, and casinos. The items described include black-and-white photographic prints, postcards, and negatives; items listed are photographic prints unless otherwise specified.

The locations in Southern Nevada and the Southwestern United States photographs depict people in Southern Nevada and the Southwestern United States from approximately 1900 to 1975. The photographs include politicians and engineers investigating the Colorado River for the future sight of the Hoover (Boulder) Dam in Black Canyon; Hoover Dam workers and construction; the towns of Goodsprings, Beatty, and Indian Springs in Nevada; the Grand Canyon in Arizona; and Mount Charleston in Nevada. The items described include black-and-white photographic prints, postcards, and negatives; items listed are photographic prints unless otherwise specified.

The group and club photographs depict social groups in Las Vegas, Nevada and other places from approximately 1860 to 1970. The groups include the Mesquite Club, the Theodore Roosevelt advocacy society "Teddy's Terrors," the Wednesday Pan Club, and the U-Wah-Un Study Group.