The Southern and Central Nevada photographs depict locations in Southern and Central Nevada from 1890 to 1950. The photographs depict mining operations, mills, animal freight teams, the Colorado River, Euro-American settlers, Valley of Fire, and Native Americans. The photographs also depict the towns of Boulder City, Goodsprings, St. Thomas, Callville, and Moapa. The items described include black-and-white photographic prints, postcards, and negatives; items listed are photographic prints unless otherwise specified. Numbered items inside oversized boxes are photographs within scrapbooks and have been digitized.

The Hoover Dam and Colorado River photographs depict the Hoover (Boulder) Dam and the Colorado River from 1925 to 1960. The photographs primarily depict the Hoover Dam following its completion in 1935, but also show the dam'’s construction and location in Black Canyon on the Colorado River. The photographs also depict Lake Mead, the reservoir created by the Hoover Dam, as well as Boulder Canyon. The items described include black-and-white photographic prints, postcards, and negatives; items listed are photographic prints unless otherwise specified.

The Las Vegas Valley photographs depict buildings and people in the Las Vegas Valley in Nevada from 1905 to 1919 and from 1940 to 1999. The photographs depict students at Nevada Southern University (predecessor of the University of Nevada, Las Vegas), the city of Las Vegas, and plants in Henderson, Nevada and Apex, Nevada.

The Laughlin, Nevada photographs depict the town of Laughlin, Nevada from 1970 to 1990. The photographs primarily depict hotels and casinos, the Laughlin Community Center, and ferries on the Colorado River. The photographs also depict Don Laughlin, the entrepreneur who purchased the land where Laughlin is located.