This series contains rapidly captured Twitter data collected from March 2020 to June 2021 in response to the COVID-19 pandemic. Twitter data were captured using a data-mining process deployed from Rapidminer Studio using a developer’s token to access Twitter’s standard search API. Data was collected from the official Twitter accounts for UNLV (@UNLV) and the governor’s office (@GovSisolak). Twitter data were also captured to represent the impact of the pandemic on individuals and businesses in the Las Vegas Valley by using the following search strings filtered by a 100 mile radius around Clark County, Nevada: #vegassafe, #vegasshutdown, #COVID-19, #COVID19, #Coronavirus, #StayHomeforNevada.