The Las Vegas, Nevada Gay, Lesbian, Bisexual, Transgender, and Queer/Questioning (LGBTQ) Collection documents the social and political activities of Las Vegas, Nevada's LGBTQ community from 1955 to 2020. The collection includes hundreds of newspaper articles about LGBTQ issues, ranging from AIDS to Nevada legislation. The collection also documents the presence of the LGBTQ community in Las Vegas, including material from gay bars, nightclubs, social clubs, advocacy and political organizations, entertainers, and student groups. Previously known as the Las Vegas Gay, Lesbian, Bisexual, and Transgender Collection.

The David G. Malcolm Papers (1942-1971) contains information on Basic Magnesium, Incorporated (BMI), Nevada Gaming laws and regulations, and a motor home organization titled Vegas Vagabonds. Included are correspondence, original papers for the purchase of land for BMI, newspaper clippings, BMI newsletters, statistical data from the Chamber of Commerce, and miscellaneous gaming information.

The collection is comprised of the personal, professional and business papers of Dr. Juanita Greer White from 1927 to 1980. Included are correspondence, booklets, dissertations, minutes, newsletters, newspaper clippings, and various other materials linked to women's organizations and Nevada organizations relating to education, health, and aging. Other material includes documents from her work in the Nevada State Legislature, books, catalogs, chemistry papers, plaques, and campaign materials.

The Frank F. Watts Collection of Casino Memorabilia (1880-1990) consists of gaming tokens and chips, matchbooks, and other memorabilia from Nevada and international casinos. The collection also contains items related to early Northern Nevada history including a salt ledger from 1880 as well as a wanted poster from 1913.

The Nevada Banking History Collection (1870-1976), compiled by the First National Bank of Nevada, ontains correspondence, checks, deposit slips and other documents related to early bank operations in Nevada. There are also newspaper articles, published materials and photographs relating to the history of banks in Nevada from 1870 to 1976.

The Clarabelle Decker Papers (1926-1980) reflect the varied career of Clarabelle Decker as a teacher, librarian, and writer who worked in Nevada, Northern Arizona, and Southern California. Materials include Decker's writings and other published works, including books, booklets, poetry, as well as teaching aids, a grammar guide, posters, and fliers. Teaching materials primarily date from 1926 to 1952, while her library and writing materials date from 1954 to 1980.

The Thomas Hickey Political Papers (1964-1996) contain the professional files of Hickey’s career as a Nevada State Assemblyman and Senator. Materials include constituent correspondence, voting records, memoranda, newspaper clippings, bills, and research documentation on topics such as the Yucca Mountain Nuclear Waste Repository, the Equal Rights Amendment (ERA), education, health, prisons, finance, and Nevada infrastructure. The collection highlights Hickey’s role on committees including finance, transportation, government affairs, and ways and means.