Southern Nevada event, tourism, and advertisement series include posters from Southern Nevada organizations and local businesses promoting the city of Las Vegas, natural tourist locations surrounding Las Vegas, merchandise sales, and special events such as marathons, political rallies, and public celebrations from 1891 to 2002, with a focus between 1975 and 2002.

Political campaign and activism posters include material from political candidates running in the city of Las Vegas and the state of Nevada from 1940 to 1974. Also included are posters from local- and state-level organizations promoting political candidates, policies, legislation, and issues associated with civil rights, labor laws, and education.