The Ferron and Bracken Photograph Collection depicts Southern and Central Nevada and other western states from 1890 to 1961. The photographs primarily depict the development and growth of early Las Vegas, Nevada; mines and mining operations in Southern and Central Nevada; towns and mines in Nevada; and the Hoover (Boulder) Dam and the Colorado River.

The Squires Family Photographs document the Squires Family and the development of the Las Vegas Valley in Nevada from approximately 1860 to 1980, with a bulk of the photographs depicting people and events from 1900 to 1950. The photographs depict the Euro-American settlement and growth of Las Vegas, Nevada; traveling and exploration of Southern Nevada and the Southwestern United States; the Hoover (Boulder) Dam and the Colorado River; clubs and social groups; and the Squires Family, especially prominent newspaper editor and publisher Charles Pember (C. P. or “Pop”) Squires, Delphine “Mom” Anderson Squires, and their children.

The Betty Ham Dokter Photographs depict the Ham Family from 1850 to 1976. The materials include photographs of the family after they moved to Las Vegas, Nevada in 1916 and document the early growth of the city. The materials also include photographs of the Colorado River, the Hoover (Boulder) Dam site before and after its construction, dinner parties, family photographs, and citizens of the Las Vegas area. The materials also include photographs of Alta Mereness Ham, Betty Ham Dokter's mother, on the set of the film Water.

The Fred and Maurine Wilson Photograph Collection depicts the Wilson Family, events, and locations in Las Vegas, Nevada and the Southwestern United States from approximately 1860 to 1990. The photographs primarily depict early Las Vegas, including the Mormon Fort and Kiel Ranch; mines, towns, and railroads in Southern Nevada; the construction and planning of the Hoover (Boulder) Dam on the Colorado River; and the Wilson Family. The photographs also include prominent Las Vegas families such as the Park Family, aerial photographs of the city, landmarks on Fremont Street and downtown Las Vegas, and desert landscapes.

The Virginia "Teddy" Fenton Photograph Collection on the Hoover Dam and Boulder City, Nevada (1920-1985) contains photographs of the Hoover Dam, Colorado River, and Boulder City, Nevada. The photographs depict the construction of the Hoover Dam from 1931 to 1936, views of the dam after it was finished, and workers building the dam.

The Alice Lake-Rockwell and Earl Rockwell Photographs depict the Las Vegas, Nevada area from approximately 1880 to 1962. The photographs primarily depict the Lake-Rockwell Family in Las Vegas, including Earl Rockwell with a local baseball team, the Las Vegas Volunteer Fire Department, and the Las Vegas Police. Other photographs include the Hoover (Boulder) Dam construction site and views of the completed dam. The photographs also portray family members from the Rockwell Family.

The Union Pacific Railroad Photographs depict the Union Pacific Railroad Company's tracks, depots, locomotives, and stations in Southern Nevada and Southern California from 1904 to 1973. The photographs primarily depict Union Pacific officials in Las Vegas, Nevada, construction of Boulder City, Nevada and the Hoover (Boulder) Dam, hotels and casinos in Las Vegas, and the aftermath of flooding in 1938 that damaged Union Pacific tracks.